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Beljanski® ingredient

What Is Pao Pereira? Uses, Flavopereirine & the Beljanski Extract

Pao pereira (Geissospermum laeve, historically known as Geissospermum vellosii) is a South American tree whose bark naturally contains distinctive alkaloids, including flavopereirine.

Molecular biologist Mirko Beljanski, PhD investigated Pao pereira extensively and developed a specific method of extraction and standardization that remains at the heart of Maison Beljanski’s Pao pereira products today.

Also spelled Pau pereira and sometimes sold simply as “Pao pereira herb,” the Beljanski® extract is the primary botanical in Pao V® and Pao V “FM”®, and a component of Womabel®, Prostabel® and OnKobel-Pro®.

Pao pereira tree canopy with a botanical illustration of its leaves and flowers
Geissospermum laeveApocynaceae · syn. G. vellosii Native to
South America
  • Documented in Brazilian literature since 1848
  • Bark contains flavopereirine, a beta-carboline alkaloid
  • Extraction method developed through Mirko Beljanski’s work
  • Independently tested for flavopereirine by HPLC
  1. 19th centuryPao pereira enters Brazilian medical and botanical literature.
  2. 1848Ezequiel Corrêa dos Santos presents Monographia do Geissospermum vellosii vulgo Pao Pereira to the Faculty of Medicine of Rio de Janeiro.
  3. A century laterMirko Beljanski, PhD turns his attention to the botanical and its naturally occurring alkaloids.
  4. TodayHis method of extraction and standardization remains at the heart of Maison Beljanski’s Pao pereira products.

History

A Botanical With More Than 175 Years of Documented History

Pao pereira—also spelled Pau-pereira—has been documented in Brazilian medical and botanical literature since the nineteenth century.

In 1848, Ezequiel Corrêa dos Santos presented Monographia do Geissospermum vellosii vulgo Pao Pereira to the Faculty of Medicine of Rio de Janeiro.

More than a century later, Mirko Beljanski, PhD turned his attention to this remarkable botanical and its naturally occurring alkaloids.

Uses

How Is Pao Pereira Used?

Most people who look up Pao pereira want to know what it is used for. There are three different answers, and it helps to keep them apart.

Traditionally

In Brazil and neighbouring countries the bark has been prepared as a decoction for centuries. Ezequiel Corrêa dos Santos documented it in his 1848 thesis, and a 1942 Brazilian review listed Pao pereira among the ten most useful trees native to the country.

In dietary supplements today

Maison Beljanski prepares a standardized Pao pereira bark extract to the specifications developed through Mirko Beljanski’s work, tested for flavopereirine. It is the main botanical in Pao V® and Pao V “FM”®, and is combined with other Beljanski® botanicals in Womabel®, Prostabel® and OnKobel-Pro®. Suggested use is printed on each label.*

In scientific research

The Beljanski Foundation, a nonprofit, has supported laboratory and preclinical studies of the Pao pereira extract at universities including Columbia University and the University of Kansas Medical Center. That research concerns the extract under defined experimental conditions, not any finished product.

Browse the published research

If you are considering a Pao pereira supplement, talk to a healthcare practitioner first, especially if you are pregnant, nursing, taking medication or have a medical condition.

flavo­pereirineBeta-carboline alkaloid · Pao pereira bark

What Is Flavopereirine?

Flavopereirine is a naturally occurring beta-carboline alkaloid found in Pao pereira bark.

Mirko Beljanski identified flavopereirine as an important component of Pao pereira and investigated it extensively as part of his work with the botanical.

Today, flavopereirine content is one of the markers Maison Beljanski uses to evaluate the identity and consistency of its Pao pereira extracts.

Independent testing · 2026

Not All Pao Pereira Extracts Are the Same

The words “Pao pereira” on a label do not necessarily tell you what is actually in the extract.

In 2026, The Beljanski Foundation purchased commercially available Pao pereira products at different price points and commissioned independent laboratory testing of their flavopereirine content by HPLC.

Flavopereirine was not detected in any of the five competitor samples. Pao V® tested at 850 ppm of flavopereirine and Pao V “FM”® at 1,144 ppm.

Flavopereirine content by product (ppm), independent HPLC testing, 2026

  • Maison Beljanski
  • Other brands · ND = not detected
  1. Pao V “FM”® Maison Beljanski · lot 11AU6CO1 1,144 ppm
  2. Pao V® Maison Beljanski · lot 10CU5E01 850 ppm
  3. Pao Pereira Graviola Welbuda · lot MI/WPAPE18C05/1-100 ND
  4. PP40 SuperSmart · lot L14643 ND
  5. Pau D’Arco Astragalus Vinatura · lot AS052124-1 ND
  6. Pao Pereira Extract Florida Herbal Pharma · lot X0037DBHE1 ND
  7. Pau Pereira (Geissospermum Vellosii) Rain Forest Pharma · lot 0140426 ND
Independent HPLC analysis by Alkemist Labs, commissioned by The Beljanski Foundation, 2026. Pao V® lot 10CU5E01 (850 ppm); Pao V “FM”® lot 11AU6CO1 (1,144 ppm). ND = not detected by the analytical method used. Results apply to the specific samples and lots tested. Certificates of analysis are held by The Beljanski Foundation.
View as a table
ProductBrand · lotFlavopereirine
Pao V “FM”®Maison Beljanski · lot 11AU6CO11,144 ppm
Pao V®Maison Beljanski · lot 10CU5E01850 ppm
Pao Pereira GraviolaWelbuda · lot MI/WPAPE18C05/1-100ND
PP40SuperSmart · lot L14643ND
Pau D’Arco AstragalusVinatura · lot AS052124-1ND
Pao Pereira ExtractFlorida Herbal Pharma · lot X0037DBHE1ND
Pau Pereira (Geissospermum Vellosii)Rain Forest Pharma · lot 0140426ND

Rather than relying solely on the botanical name, Maison Beljanski pays particular attention to the botanical species, extraction process, chemical profile and independent testing of its Pao pereira.

Quality

The Beljanski Standard

Correct Botanical Identity

Geissospermum laeve / Geissospermum vellosii

Distinctive Extraction

Prepared according to specifications inspired by the methods developed through Mirko Beljanski’s work.

Flavopereirine Content

Measured as an important marker of the extract’s botanical profile and consistency.

Independent Testing

Beljanski® products are tested by an independent third-party laboratory before release by Quality Control.

Responsible Sourcing

Carefully sourced in South America with attention to responsible harvesting practices.

Local harvesters carrying woven baskets on a mule in South America

Responsibly Harvested

The bark of Pao pereira naturally sheds and regenerates, allowing it to be collected without cutting down the tree.

This natural renewal makes responsible harvesting possible while preserving the tree for future growth.

Beljanski® products

Choose Your Pao Pereira Formula

Pao V® bottle

Pao V®

Pao Pereira

Maison Beljanski’s signature Pao pereira extract in a stand-alone formula.

Discover Pao V®
Womabel® bottle

Womabel®

Pao Pereira + Rauwolfia Vomitoria + OnkoTea®

A three-botanical formula designed specifically for women’s wellness.*

Discover Womabel®
Prostabel® bottle

Prostabel®

Pao Pereira + Rauwolfia Vomitoria

A botanical formula designed specifically for men’s wellness.*

Discover Prostabel®

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Good to know

Frequently Asked Questions

Still have a question about Pao pereira? Talk to our team

What is Pao pereira?

Pao pereira is a South American tree in the Apocynaceae family. Its bark contains naturally occurring alkaloids, including flavopereirine, and has a long history of traditional use.

What is Pao pereira used for?

Traditionally, the bark has been prepared as a decoction in South America. Today it is used as a standardized bark extract in Beljanski® dietary supplements such as Pao V®, and as a research material in university laboratory studies. Suggested use for each supplement is given on its label.

How Pao pereira is used

Is Pao pereira the same as Pau d’arco?

No. They are different trees. Pao pereira (Geissospermum laeve, also spelled Pau pereira) belongs to the Apocynaceae family. Pau d’arco (Handroanthus impetiginosus, formerly Tabebuia) belongs to the Bignoniaceae family. Beljanski® products contain Pao pereira, not Pau d’arco.

Is Pao pereira the same as Geissospermum vellosii?

Yes. The botanical has been known historically as Geissospermum vellosii. Current botanical sources also identify it as Geissospermum laeve. Both names therefore appear in scientific and botanical literature.

What is flavopereirine?

Flavopereirine is a naturally occurring beta-carboline alkaloid found in Pao pereira. Maison Beljanski uses flavopereirine content as one of the markers for evaluating the botanical profile and consistency of its Pao pereira extracts.

Are all Pao pereira extracts the same?

No. Products can differ in botanical identity, extraction method and chemical profile. In independent HPLC testing commissioned by The Beljanski Foundation in 2026, flavopereirine was not detected in any of five competitor products sold as Pao pereira, while Pao V® and Pao V “FM”® tested at 850 and 1,144 ppm.

See the comparison

How is Maison Beljanski’s Pao pereira tested?

Beljanski® products undergo independent third-party laboratory testing before being released by Quality Control, including HPLC analysis of flavopereirine content.

Are there precautions when taking Pao pereira?

Follow the suggested use on the product label. Consult a healthcare practitioner before use if you are pregnant, nursing, have a medical condition or are taking prescription medication. Beljanski® product labels also advise not taking silica at the same time as Pao pereira.

Where can I buy Pao pereira?

Maison Beljanski sells its Pao pereira extract directly at maisonbeljanski.com in Pao V®, Pao V “FM”®, Womabel® and Prostabel®. OnKobel-Pro® is available through qualified healthcare professionals.

Choose your Pao pereira formula
Mirko Beljanski, PhD, in his laboratory holding a pipette
Mirko Beljanski, PhD (1923–1998), molecular biologist.

The Botanical Legacy of Mirko Beljanski

Mirko Beljanski’s investigation of Pao pereira was part of a scientific career spanning nearly five decades and 133 scientific publications.

His work on DNA, RNA and naturally occurring compounds ultimately led him to develop the distinctive botanical extracts that inspired today’s Beljanski® products.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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